Haematological Evaluation of Mycobacterium tuberculosis Subjects at Central Hospital Agbor, Nigeria

Tuberculosis (TB) is a severe public health problem in Nigeria that caused by Mycobacterium tuberculosis and has its attendant effects. The aim of this study was to evaluate the haematological profile 146 newly diagnosed patients with attending Central Hospital Agbor, Delta State. A total 38 negative individuals were monitored as control. Five millilitres venous blood collected into EDTA containers. Complete count (Packed cell volume (PCV), haemoglobin, white count, lymphocyte, platelet neutrophil counts) estimated using Sysmex XP 300 – haematology analyser. SPSS used analyse data. There no significant difference (p>0.05) observed counts between subjects control subjects. had significantly lower (p <0.05) haemoglobin levels (9.81 ± 0.24) than (12.08 0.42). higher among (314.09 21.84) controls (279.35 20.29). lymphocyte (%) < 0.05) controls; (54.78 2.64) (49.28 2 .73). differences >0.05) mean when compared. However, there concentration tuberculosis-associated complications. compared Neutrophil Lymphocyte Ratio (NLR) Platelet-Lymphocyte (PLR) controls. abnormalities area. identified NLR PLCR novel biomarkers for monitoring systemic inflammation tuberculosis. It therefore pertinent estimate parameters early help informed clinical decision making management these